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Dating of Salt Intake and you may Hypertension May differ That have Energy Intake

Dating of Salt Intake and you may Hypertension May differ That have Energy Intake

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Regarding Division of Epidemiology, Company regarding Treatments (Meters.An excellent.Yards., T.G., M.Meters.) and Agencies away from Diet and you can Integrative Structure (P.Yards.Grams.), School from Utah, Salt River Urban area; Service away from Drug, Ny University University from Medicine (J.Meters.B.); Welch Cardiovascular system to possess Reduction, Epidemiology and you may Medical Search, Johns Hopkins College or university, Baltimore, MD (L.J.An effective.); and you will Agency regarding Biostatistical Sciences, Wake Tree School out of Medication, Winston-Salem, NC (J.A beneficial.T.).

You’re viewing the most up-to-date type of this informative article. Previous versions:

Regarding Section away from Epidemiology, Department of Treatments (Meters.Good.M., T.G., M.Meters.) and Institution off Nourishment and Integrative Anatomy (P.Yards.Grams.), University from Utah, Sodium River Area; Department out of Treatments, Nyc School College or university from Medication (J.Yards.B.); Welch Heart to have Cures, Epidemiology and you may Health-related Browse, Johns Hopkins College or university, Baltimore, MD (L.J.A.); and you will Agencies off Biostatistical Sciences, Wake Tree School from Medication, Winston-Salem, NC (J.Good.T.).

You’re watching the newest types of this short article. Previous versions:

On the Office out-of Epidemiology, Agencies out of Treatments (Yards.A.M., T.Grams., Meters.M.) and you will Department from Diet and Integrative Physiology (P.M.Grams.), College of Utah, Salt River Town; Department from Medicine, Nyc University University from Treatments (J.Yards.B.); Welch Cardio having Cures, Epidemiology and Medical Look, Johns Hopkins School, Baltimore, MD (L.J.An excellent.); and you can Institution from Biostatistical Sciences, Aftermath Forest University of Medicine, Winston-Salem, NC (J.An excellent.T.).

You’re watching the newest variety of this information. Earlier incarnations:

Regarding Division of Epidemiology, Institution regarding Drug (M.A beneficial.Yards., T.Grams., Yards.Yards.) and you will Service out-of Diet and you can Integrative Anatomy (P.Yards.G.), College or university from Utah, Salt Lake Town; Service out-of Drug, Nyc College College or university from Medicine (J.Meters.B.); Welch Center to possess Protection, Epidemiology and Health-related Research, Johns Hopkins School, Baltimore, MD (L.J.A beneficial.); and you will Company out-of Biostatistical Sciences, Aftermath Tree School away from Drug, Winston-Salem, NC (J.A good.T.).

You’re enjoying the most recent sort of this informative article. Previous versions:

Regarding Section from Epidemiology, Institution regarding Medicine (Yards.A.M., T.Grams., Meters.Yards.) and you may Department from Diet and Integrative Physiology (P.M.Grams.), University out-of Utah, Salt River City; Service out of Treatments, New york College or university College regarding Medicine (J.Yards.B.); Welch Heart to possess Protection, Epidemiology and you can Health-related Browse, Johns Hopkins School, Baltimore, MD (L.J.An effective.); and you will Service out-of Biostatistical Sciences, Wake Forest College out-of Treatments, Winston-Salem, NC (J.An effective.T.).

You are enjoying the newest variety of this post. Earlier incarnations:

About Division away from Epidemiology, Agencies regarding Medication (Meters.A.M., T.Grams., Yards.M.) and you may Institution regarding Nourishment and you may Integrative Anatomy (P.Meters.G.), University of Utah, Salt Lake City; Agency away from Drug, Ny College School off Medication (J.M.B.); Welch Cardio to own Protection, Epidemiology and Logical Look, Johns Hopkins College or university, Baltimore, MD (L.J.A beneficial.); and you will Agencies out-of Biostatistical Sciences, Wake Tree College out of Treatments, Winston-Salem, NC (J.A good.T.).

You’re watching the most recent type of this informative article. Earlier versions:

Regarding Office off Epidemiology, Agencies away from Medicine (M.A great.Meters., T.G., Meters.Yards.) and you will Agency regarding Diet and you may Integrative Anatomy (P.Meters.G.), School regarding Utah, Salt Lake Town; Department of Treatments, Ny College or university College of Medication (J.M.B.); Welch Heart getting Prevention, Epidemiology and you may Scientific Browse, Johns Hopkins University, Baltimore, MD (L.J.Good.); and Department out of Biostatistical Sciences, Aftermath Forest University away from Drug, Winston-Salem, NC (J.Good.T.).

Abstract

Dietary Na recommendations are expressed as absolute amounts (mg/d) rather than as Na density (mg/kcal). Our objective was to determine whether the strength of the relationship of Na intake with amino sign in blood pressure (BP) varied with energy intake. The DASH (Dietary Approaches to Stop Hypertension)–Sodium trial was a randomized feeding trial comparing 2 diets (DASH and control) and 3 levels of Na density. Participants with pre- or stage 1 hypertension consumed diets for 30 days in random order; energy intake was controlled to maintain body weight. This secondary analysis of 379 non-Hispanic black and white participants used mixed-effects models to assess the association of Na and energy intakes with BP. The relationships between absolute Na and both systolic and diastolic BP varied with energy intake. BP rose more steeply with increasing Na at lower energy intake than at higher energy intake (P interaction<0.001). On the control diet with 2300 mg Na, both systolic and diastolic BP were higher (3.0 mm Hg; 95% confidence interval, 0.2–5.8; and 2.7 mm Hg; 95% confidence interval, 1.0–4.5, respectively) among those with lower energy intake (higher Na density) than among those with higher energy intake (lower Na density). The association of Na with systolic BP was stronger at lower levels of energy intake in both blacks and whites (P<0.001). The association of Na and diastolic BP varied with energy intake only among blacks (P=0.001). Sodium density should be considered as a metric for expressing dietary Na recommendations.

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